Major medical centers in the United States and around the world endorse reflexology for a growing number of conditions. A partial list includes:

Maryland Center for Integrative Medicine says:
The benefits (of reflexology) include reduction in tension and stress, increased vascular, neural and lymphatic circulation, and the releasing of toxins. Research has shown that blood pressure can actually decrease during a session! Clients use reflexology to alleviate or manage asthma, sinus problems, digestive disorders, inflammations, menstrual irregularities, pain, fatigue, inflammatory skin conditions and other imbalances. It is especially beneficial for circulatory problems.

St. Rita's Medical Center
conducted a three-month pilot study on open-heart patients who received reflexology, and the study confirmed a patient's level of pain and anxiety decreased significantly. It also helped patients increase the distance they were able to walk, decreased the number of days they were hospitalized and the amount of medication administered during their recovery process.

The DeKalb Medical Center says:
During the session, specific reflex areas on the feet, hands and ears to encompass a complete method of promoting stress reduction, circulation, balance, vitality and normal body functioning, as well as enhancing relaxation and an overall sense of health and well-being.

The University of Pittsburgh Medical Center poses and answers the question:
What are the indications for reflexology? Reflexology is a form of preventive medicine that aims to maintain a person's balance and well being. Conditions treated may include: migraine headache, hypertension, menstrual cramps or irregularities, myofascial pain, fibromyalgia, insomnia and anxiety disorders.

Beebe Medical Center says:
May help relieve stress, improve circulation, relieve stiffness and reduce pain. Also for PMS, osteoarthritis, rheumatoid arthritis and Raynaud's phenomenon.